Impaired intracellular calcium transfer affecting Natural Killer cells in ME

Bar graphs representing TRPM3 current amplitude at + 100 mV after stimulation with 100 μΜ PregS in CFS/ME patients at just over 5. Healthy controls at around 12.5

by Sasha Nimmo Australian scientists at the National Centre for Neuroimmunlogy and Emerging Diseases at Griffith University published a new paper on reduced intracellular calcium mobilisation in Natural Killer (NK) immune cells and Transient Receptor Potential Melastatin 3 (TRPM3) cation channels. Authors say it 'could suggest potential therapeutic targets and/or prognostic markers'. 'Loss of Transient Receptor … Continue reading Impaired intracellular calcium transfer affecting Natural Killer cells in ME

Calcium channel ion defects: research from Australia’s Griffith Uni

Minister Enoch with NCNED researchers in lab looking happy

by Sasha Nimmo Queensland's Griffith University is home to the National Centre for Neuroimmunology and Emerging Diseases (NCNED), one of the leading centres for research in ME and chronic fatigue syndrome.  They've been in the news lately for their patented biomarker discovery on calcium channel ion defects in patients. The words 'breakthrough' and 'finally' have … Continue reading Calcium channel ion defects: research from Australia’s Griffith Uni

Gene differences found in severe Myalgic Encephalomyelitis patients

Queensland scientists looked at patients with moderate and severe Myalgic Encephalomyelitis (International Consensus Criteria). In the severe ME patients, they found 37 genes were significantly upregulated and 55 genes were significantly downregulated compared with nonfatigued controls. However, there was no difference in expression of protein kinase genes between moderate ME patients and controls.

Study shows immune differences in moderate and severe chronic fatigue syndrome (Fukuda criteria)

by Sasha Nimmo An Australian university’s longitudinal study into immune changes in people with chronic fatigue syndrome (CFS) may lead to diagnostic test. Griffith University researchers have looked at the immune systems of patients with moderate and severe CFS (1994 Fukuda criteria) once, then again six months later. The study has just been published in the Journal of … Continue reading Study shows immune differences in moderate and severe chronic fatigue syndrome (Fukuda criteria)