By Sasha Nimmo An international collaboration of scientists, including Fane Mensah, Dr Jo Cambridge and Australian Dr Chris Armstrong investigated the relationship between CD24 expression and B cell maturation and found CD24 expression on B cells is related to energy metabolism and that its role differs between B cell subsets. ‘CD24 Expression and B Cell … Continue reading Study examines link between immune dysfunction and metabolism in ME
Macquarie University are recruiting people with chronic fatigue syndrome, fibromyalgia, gastrointestinal disorders and multiple chemical sensitivity for a study measuring somatic symptoms, hypochondria, anxiety and depression, catastophising and co-morbid diseases.
European researchers have examined the evidence that ME may be an autoimmune disease, stating "disease onset is often reported to be triggered by infections and the link between infections and autoimmune diseases is well established". A group of German scientists tested this theory, using a process called immunoadsorption to remove antibodies in 10 people with ME.
by Sasha Nimmo Australian scientists at the National Centre for Neuroimmunlogy and Emerging Diseases at Griffith University published a new paper on reduced intracellular calcium mobilisation in Natural Killer (NK) immune cells and Transient Receptor Potential Melastatin 3 (TRPM3) cation channels. Authors say it 'could suggest potential therapeutic targets and/or prognostic markers'. 'Loss of Transient Receptor … Continue reading Impaired intracellular calcium transfer affecting Natural Killer cells in ME
by Sasha Nimmo Australian researchers have literally measured how long people with Myalgic Encephalomyelitis can stand up. The study shows the length of time patients can stand up may be a useful measure of ME severity, and easy to do in clinical environments. The study also confirmed an earlier finding that Activin B is a … Continue reading How much can people with ME stand?
by Sasha Nimmo Scientists from Australia's Griffith University found 'a significant reduction of glycolytic reserve in resting natural killer (NK) cells' from people with Myalgic Encephalomyelitis (ICC ME) compared with healthy controls. "These findings suggest resting NK cells from ME/CFS patients have reduced ability to increase glycolytic flux to respond to high energetic demands for … Continue reading Study finds reduced ability to respond to energy demands in ME patients’ immune systems
by Sasha Nimmo A new study published in the prestigous journal, Nature, examined the metabolism of people with ME and/or chronic fatigue syndrome and looked at irritable bowel syndrome (IBS), finding differences between patients and controls as well as patient subgroups with and without IBS. It also confirmed earlier metabolic studies. The study, 'Insights into … Continue reading Nature journal publishes metabolism study
by Sasha Nimmo University of Sydney's Dr Sonia Lee looked at selective reporting in Myalgic Encephalomyelitis and chronic fatigue syndrome research. The study found psychosocial trials on ME and CFS are more likely to engage in selective reporting - meaning they are a waste of research funds and time - than cellular trials. The small … Continue reading Research waste in ME and CFS trials
by Sasha Nimmo Scientists at Queensland's National Centre for Neuroimmunology and Emerging Diseases, Griffith University found obvious differences between the brains of patients with chronic fatigue syndrome and healthy controls, when examined using magnetic resonance imaging (MRI) during an attention test. The study examined 43 people with chronic fatigue syndrome (Fukuda criteria) and 26 healthy … Continue reading Brain differences shown in chronic fatigue syndrome (Fukuda) study
By Sasha Nimmo Most of Australia's medical research funding for ME and CFS comes from the Mason Foundation, who are currently looking at whether they will fund a biobank or a patient registry for Myalgic Encephalomyelitis and/or chronic fatigue syndrome samples. Last week the Mason Foundation updated stakeholders on the decision-making process. This is important … Continue reading Mason Foundation explores ME and CFS biobank for Australia